Elenco Pubblicazioni

ELENCO PUBBLICAZIONI

1. Amerini S., Rubino A., Filippi S., Ledda F. & Mantelli L.
   Modulation by adrenergic transmitters of the efferent function of capsaicin-sensitive nerves in cardiac tissue.
   Neuropeptides 20, 225-232, 1991.
2. Amerini S., Rubino A., Mantelli L., Filippi S. & Ledda F.
   The inhibitory effect of opioid and -adrenoceptor agonist on cardiac sensory neurones is pertussis toxin-insensitive.
   Eur. J. Pharmacol., 216, 445-448, 1992.
3. Mantelli L., Amerini S., Filippi S. & Ledda F.
   Positive inotropic effects of CGRP and isoprenaline: analogies and differences.
   Neuropeptides, 23, 193-198, 1992.
4. Ledda F., Amerini S., Filippi S., Mantelli L., Morbidelli L., Rubino A. & Ziche M.
   Cardiovascular effects of capsaicin-sensitive neurons.
   Cardioscience, 4, 1-7, 1993.
5. Mantelli L., Amerini S., Filippi S. & Ledda F.
   Modulation of adrenergic responses by prostanoids in isolated mesenteric vascular bed of the rat.
   Gen. Pharmacol., 24, 911-919, 1993.
6. Mantelli L., Amerini S., Filippi S. & Ledda F.
   Blockade of adenosine receptors unmask a stimulatory effect of ATP on cardiac contractility.
   Br. J. Pharmacol., 109, 1268-1271, 1993.
7. Amerini S., Mantelli L., Filippi S. & Ledda F.
   Age-dependent modifications of the role of prostanoids in cardiac preparations of normotensive and hypertensive rats.
   Pharmacol. Res., 28, 341-350, 1993.
8. Amerini S., Mantelli L., Filippi S. & Ledda F.
   Effects of aging and hypertension on the vasorelaxant activity of calcitonin gene-related peptide: a comparison with other vasodilator agents.
   J. Cardiovasc. Pharm., 23, 432-437, 1994.
9. Amerini S., Filippi S., Parenti A., Ziche M. & Ledda F.
   Thapsigargin inhibits the response to acetylcholine and substance P but does not interfere with the response to the endothelium-independent agents.
   J. Cardiovasc. Pharm., 28, 82-88, 1996.
10. Amerini S., Filippi S., Parenti A., Ledda F. & Ziche M.
    Vasorelaxant effects induced by the antiangiogenic drug Linomide in aortic and saphenous vein preparations of the rabbit.
    Br. J. Pharmacol., 122, 1739-1745, 1997.
11. Mancina R., Barni T., Calogero A.E., Filippi S., Amerini S., Peri A., Susini T., Vannelli G.B., Burrello N., Forti G. & Maggi M.
    Identification, characterization, and biological activity of endothelin receptors in human ovary.
    J. Clin. Endocr. Metab., 82, 4122-4129, 1997.
12. Filippi S., Amerini S., Maggi M., Natali A. & Ledda F.
    Studies on the mechanisms involved in the ATP-induced relaxation in human and rabbit corpus cavernosum.
    J. Urology, 161, 326-331, 1999.
13. Parenti A., Filippi S., Amerini S., Granger H.J., Fazzini A. & Ledda F.
    Inositol phosphate metabolism and NO-synthase activity in endothelial cells are involved in the vasorelaxant activity of nebivolol.
    J. Pharmacol. Exp. Ther., 292, 698-703, 2000.
14. Maggi M., Filippi S., Ledda F., Magini A. & Forti G.
    Erectile dysfunction: from biochemical pharmacology to advances in medical therapy (invited review).
    Eur. J. Endocrinol., 143, 143-154, 2000.
15. Filippi S., Mancini M., Amerini S., Bartolini M., Natali A., Mancina R., Forti G., Ledda F. & Maggi M.
    Functional adenosine receptors in human corpora cavernosa.
    Int. J. Androl., 23, 210-217, 2000.
16. Chiarugi A., Dello Sbarba P., Paccagnini A., Donnini S., Filippi S. & Moroni F.
    Combined inhibition of indoleamine 2,3-dioxygenase and nitric oxide synthase modulates neurotoxin release by interferon--activated macrophages.
    J. Leukocyte Biol., 68, 260-266, 2000.
17. Filippi S., Parenti A., Donnini S., Granger H.J., Fazzini A. & Ledda F.
    Alpha-1D adrenoceptors cause endothelium-dependent vasodilatation in the rat mesenteric vascular bed.
    J. Pharmacol. Exp. Ther., 296: 869-875, 2001.
18. Parenti A., Brogelli L., Filippi S., Donnini S. & Ledda F.
    Effect of hypoxia and endothelial loss on vascular smooth muscle cell responsiveness to VEGF-a: role of flt-1/VEGF-receptor-1.
    Cardiovasc. Res., 55: 201-212, 2002.
19. Filippi S., Luconi M., Natali A., Tozzi P., Forti G., Ledda F. & Maggi M.
    Endothelium-dependency of yohimbine-induced corpus cavernosum relaxation.
    Inter. J. Impot. Res., 14: 295-307, 2002.
20. Filippi S., Vannelli G. B., Granchi S., Luconi M., Crescioli C., Mancina R., Natali A., Brocchi S., Vignozzi L., Bencini E., Noci I., Ledda F., Forti G. & Maggi M.
    Identification, localization and functional activity of oxytocin receptors in epididymis.
    Mol. Cell. Endocrinol., 193: 89-100, 2002.
21. Filippi S., Luconi M., Granchi S., Vignozzi L., Bettuzzi S., Tozzi P., Ledda F., Forti G. & Maggi M.
    Estrogens, but not androgens, regulate expression and functional activity of oxytocin receptor in rabbit epididymis.
    Endocrinology, 143: 4271-4280, 2002.
22. Granchi S., Vannelli G. B., Vignozzi L., Crescioli C., Ferruzzi P., Mancina R., Vinci M. C., Forti G., Filippi S., Luconi M., Ledda F. & Maggi M.
    Expression and regulation of endothelin-1 and its receptors in human penile smooth muscle cells.
    Mol. Hum. Reprod., 8: 1053-1064, 2002.
23. Filippi S., Crescioli C., Vannelli G. B., Fazzini A., Natali A., Riffaud J. P., Maggi M. & Ledda F.
    Effects of NCX 4050, a new no-donor, in rabbit and human corpus cavernosum.
    Int. J. Androl., 26: 101-108, 2003.
24. Filippi S., Vignozzi L., Vannelli G. B. , Ledda F., Forti G. & Maggi M.
    Role of oxytocin in the ejaculatory process.
    J. Endocrinol. Invest., 26 (suppl. 3): 82-86, 2003.
25. Morbidelli L., Donnini S., Filippi S., Messori L., Piccioli F., Orioli P.L., Sava G. & Ziche M.
    Antiangiogenic properties of selected ruthenium (III) complexes that are nitric oxide scavengers.
    Br. J. Cancer, 88: 1484-1491, 2003.
26. Filippi S., Marini M., Vannelli G.B., Crescioli C., Granchi S., Vignozzi L., Luconi M., Ferruzzi P., Morelli A., Forti G. , Ledda F. & Maggi M.
    Effects of hypoxia on endothelin-1 sensitivity in the corpus cavernosum.
    Mol. Hum. Repr., 9: 765-774, 2003.
27. Parenti A., Bellik L., Brogelli L., Filippi S. & Ledda F.
    Endogenous VEGF-A is responsible for the mitogenic effect of monocyte chemotactic protein-1 on vascular smooth muscle cells.
    Am. J. Physiol., 286:H1978-1984, 2004.
28. Vignozzi L., Filippi S., Luconi M., Morelli A., Marini M., Mancina R., Vannelli G.B., Granchi S., Orlando C., Gelmini S., Ledda F., Forti G. & Maggi M.
    Oxytocin receptor is expressed in the penis and mediates an estrogen-dependent smooth muscle contractility.
    Endocrinology, 145:1823-1834, 2004.
29. Morelli A., Filippi S., Mancina R., Luconi M., Vignozzi L., Marini M., Orlando C., Vannelli G.B., Aversa A., Natali A., Forti G., Giorgi M., Jannini E.A., Ledda F. & Maggi M.
    Androgens regulate phosphodiesterase type 5 expression and functional activity in corpora cavernosa.
    Endocrinology, 145:2253-2263, 2004.
30. Vignozzi L., Vannelli G.B., Morelli A., Mancina R., Marini M., Ferruzzi P., Crescioli C., Luconi M., Donati S., Fisher A., Baldi E., Filippi S., Forti G. & Maggi M.
    Identification, characterization and biological activity of oxytocin receptor in the developing human penis.
    Mol. Hum. Repr., 11: 99-106, 2005.
31. Mancina R., Filippi S., Marini M., Morelli A., Vignozzi L., Salonia A., Montorsi F., Mondani N., Vannelli G.B., Donati S., Lotti F., Forti G. & Maggi M.
    Expression and functional activity of phosphodiesterase type 5 in human and rabbit vas deferens.
    Mol. Hum. Repr., 11:107-115, 2005.
32. Zhang X.H., Filippi S., Vignozzi L., Mancina R., Luconi M., Marini M., Vannelli G.B., Forti G. & Maggi M.
    Identification, localization and functional “in vitro” and “in vivo” activity of oxytocin receptor in the rat penis.
    J. Endocrinol., 184: 567-576, 2005.
33. Zhang X.H., Morelli A., Luconi M., Vignozzi L., Filippi S., Marini M., Vannelli G.B., Mancina R., Forti G. & Maggi M.
    Testosterone Regulates PDE5 Expression and in vivo Responsiveness to Tadalafil in Rat Corpus Cavernosum.
    European Urology, 47:409-416, 2005.
34. Vignozzi L., Corona G., Petrone L., Filippi S., Morelli A.M., Forti G. & Maggi M.
    Testosterone and sexual activity.
    J. Endocrinol. Invest., 28 (Suppl. 3): 39-44, 2005.
35. Bellik L., Vinci M.C., Filippi S., Ledda F. & Parenti A .
    Intracellular pathways triggered by the selective flt-1-agonist PlGF in vascular smooth muscle cells exposed to hypoxia.
    Br. J. Pharm., 146: 568-575, 2005
36. Filippi S., Morelli A., Vignozzi L., Vannelli G.B., Marini M., Ferruzzi P., Mancina R., Crescioli C., Mondani N., Forti G., Ledda F. & Maggi M.
    Oxytocin mediates the estrogen-dependent contractile activity of endothelin-1 in human and rabbit epididymis.
    Endocrinology, 146: 3506-3517, 2005.
37. Morelli A., Filippi S., Zhang X.H., Luconi M., Vignozzi L., Mancina R. & M. Maggi.
    Peripheral regulatory mechanisms in erection.
    Int. J. Androl., 28 Suppl 2:23-27, 2005
38. A. Morelli, L.Vignozzi, S. Filippi, R. Mancina & M. Maggi.
    Erectile dysfunction: molecular biology, pathophysiology and pharmacological treatment.
    Minerva Urol Nefrol. 57(2):85-90, 2005.
39. XH Zhang, S Filippi, A Morelli, L Vignozzi, M Luconi, S Donati, G Forti & M Maggi.
    Testosterone restores diabetes-induced erectile dysfunction and sildenafil responsiveness in two distinct animal models of chemical diabetes.
    J Sex Med, 3: 253-266, 2006.
40. Vignozzi L, Filippi S, Morelli A, Ambrosini S, Luconi M, Vannelli GB, Donati S, Crescioli C, Zhang XH, Mirone V, Forti G & Maggi M.
    Effect of chronic tadalafil administration on penile hypoxia induced by cavernous neurotomy in the rat.
    J Sex Med, 3: 419-431, 2006.
41. Morelli A., Filippi S., Vignozzi L., Mancina R. & Maggi M.
    Physiology of erectile function: an update on intracellular molecular processes.
    EAU-EBU Update Series, 4: 96-108, 2006.
42. Annamaria Morelli, Linda Vignozzi, Sandra Filippi, Gabriella B. Vannelli, Stefano Ambrosini, Rosa Mancina, Clara Crescioli, Silvia Donati, Benedetta Fibbi, Enrico Colli, Luciano Adorini & Mario Maggi.
    BXL-628, a Vitamin D receptor agonist effective in benign prostatic hyperplasia treatment, prevents RhoA activation and inhibits RhoA/Rho kinase signalling in rat and human bladder.
    The PROSTATE, 67:234-47, 2007.
43. Sandra Filippi, Annamaria Morelli, Peter Sandner, Benedetta Fibbi, Rosa Mancina, Mirca Marini, Mauro Gacci, Linda Vignozzi, Gabriella Barbara Vannelli, Marco Carini, Gianni Forti & Mario Maggi.
    Characterization and functional activity of an androgen-dependent PDE5 activity in bladder.
    Endocrinology, 148:1019-29, 2007.
44. Vignozzi L, Morelli A, Filippi S, Luconi M, Ambrosini S, Mancina R, Vannelli GB, Zhang XH, Forti G & Maggi M.
    Testosterone regulates Rhoa/Rho-kinase signalling in two distinct animal models of chemical diabetes.
    J Sex Med, 4:620-32, 2007.
45. Vinci MC, Bellik L, Filippi S, Ledda F & Parenti A.
    Trophic effects induced by alpha-1D adrenoceptors on endothelial cells are potentiated by hypoxia.
    Am J Physiol Heart Circ Physiol 293:H2140-7, 2007.
46. Morelli A, Corona G, Vignozzi L, Filippi S, Forti G & Maggi M.
    Which patients with sexual dysfunction are suitable for testosterone replacement therapy?
    J Endocrinol Invest 30:880-8, 2007.
47. Fibbi B, Morelli A, Marini M, Zhang XH, Mancina R, Vignozzi L, Filippi S, Chavalmane A, Silvestrini E, Colli E, Adorini L, Vannelli GB & Maggi M.
    Atorvastatin but not elocalcitol increases sildenafil responsiveness in Spontaneously Hypertensive Rats by regulating the RhoA/ROCK pathway.
    J Androl. 29: 70-84, 2008.
48. Vignozzi L, Morelli A, Filippi S, Vannelli GB, Mungai S, Marini M, Forti G & Maggi M.
    Effect of sildenafil administration on penile hypoxia induced by cavernous neurotomy in the rat.
    Int J Impot Res 2008; 20: 60-7, 2008.
49. Morelli A, Marini M, Mancina R, Luconi M, Vignozzi L, Fibbi B, Filippi S, Pezzatini A, Forti G, Vannelli GB & Maggi M.
    Sex steroids and leptin regulate the “first kiss” (KiSS 1/GPR54 system) in human GnRH-secreting neuroblasts.
    J Sex Med 5:1097-113, 2008.
50. Annamaria Morelli, Roberta Squecco, Paola Failli, Sandra Filippi, Linda Vignozzi, Aravinda K. Chavalmane, Benedetta Fibbi, Rosa Mancina, Giorgia Luciani, Mauro Gacci, Enrico Colli, Fabio Francini, Luciano Adorini & Mario Maggi.
    The vitamin D receptor agonist elocalcitol up-regulates L-type calcium channel activity in human and rat bladder.
    Am J Physiol Cell Physiol 294: C1206-14, 2008.
51. Morelli A, Fibbi B, Marini M, Silvestrini E, De Vita G, Chavalmane Ak, Vignozzi L, Filippi S, Forti G, Vannelli GB & Maggi M.
    Dihydrotestosterone and leptin regulate gonadotropin-releasing hormone (GnRH) expression and secretion in human GnRH-secreting neuroblasts.
    J Sex Med 6: 397-407, 2009
52. Morelli A, Chavalmane Ak, Filippi S, Fibbi B, Silvestrini E, Sarchielli E, Zhang Xh, Vignozzi L, Vannelli GB, Forti G & Maggi M.
    Atorvastatin ameliorates sildenafil-induced penile erections in experimental diabetes by inhibiting diabetes-induced RhoA/Rho-kinase signalling hyper-activation.
    J Sex Med 6: 91-106, 2009.
53. Vignozzi L, Filippi S, Morelli A, Luconi M, Jannini E, Forti G & Maggi M.
    Regulation of epididymal contractility during semen emission, the first part of the ejaculatory process: a role for estrogen.
    J Sex Med. 5:2010-6; quiz 2017, 2008.
54. Vignozzi L., Filippi S., Morelli A., Marini M., Chalvamane A., Fibbi B., Silvestrini E., Mancina R., Carini M., Forti G., Vannelli GB. & Maggi M.
    Cavernous neurotomy in the rat is associated with the onset of an overt condition of hypogonadism.
    J Sex Med. 6:1270-1283, 2009.
55. Morelli A, Filippi S, Sandner P, Fibbi B, Chalvamane AK, Silvestrini E, Sarchielli E, Vignozzi L, Gacci M, Carini M, Vannelli GB & Maggi M.
    Vardenafil modulates bladder contractility through CGMP-mediated inhibition of RhoA/Rho kinase signaling pathway in spontaneously hypertensive rats.
    J Sex Med. 6:1594-1608
56. Fibbi B., Filippi S., Morelli A., Vignozzi L., Silvestrini E., Chavalmane A., De Vita G., Marini M., Gacci M., Manieri C., Vannelli GB & Maggi M.
    Estrogens regulate human and rabbit epididymal contractility through the RhoA/Rho-kinase pathway.
    J Sex Med. 8: 2173-86, 2009
57. Sandra Filippi, Linda Vignozzi, Annamaria Morelli, Aravinda K. Chavalmane, Erica Sarchielli, Benedetta Fibbi, Farid Saad, Peter Sandner, Peggy Ruggiano, Gabriella B. Vannelli, Edoardo Mannucci & Mario Maggi.
    Testosterone partially ameliorates metabolic profile and erectile responsiveness to PDE5 inhibitors in an animal model of male metabolic syndrome.
    J Sex Med , 2009 Sep 1. [Epub ahead of print]
58. Gacci M, Ierardi A, Rose AD, Tazzioli S, Scapaticci E, Filippi S, Maggi M, Nicita G, Carini M & Montorsi F.
    Vardenafil can Improve Continence Recovery after Bilateral Nerve Sparing Prostatectomy: Results of a Randomized, Double Blind, Placebo-Controlled Pilot Study.
    J Sex Med. 2009 Sep 1. [Epub ahead of print]
59. Fibbi B, Morelli A, Vignozzi L, Filippi S, Chavalmane AK, De Vita G, Marini M, Gacci M, Vannelli GB, Sandner P & Maggi M.
    Characterization of PDE5 expression and functional activity in the human male lower urinary tract.
    J Sex Med. 2009 Nov 3. [Epub ahead of print]
60. Morelli A, Filippi S, Comeglio P, Sarchielli E, Chavalmane AK, Vignozzi L, Fibbi B, Silvestrini, E, Sandner P, Gacci M, Carini M, Vannelli GB & Maggi M.
    Acute vardenafil administration improves bladder oxygenation in Spontaneously Hypertensive Rats.
    J Sex Med. 2009 Nov 3. [Epub ahead of print]